A comparative study of intranasal dexmedetomidine and intranasal midazolam for premedication - A prospective randomized double-blind study in children posted for tonsillectomy

Preanesthetic medication in paediatric patients is well known to be a challenge for anaesthesiologists. Premedication population helps produce relaxed state with reduced anxiety and increased compliance as ease separation from parent allowing the patient tolerate co-operate necessary procedure. Our aim do comparation of dexmedetomidine midazolam given via intranasal route children posted tonsillectomy premedication. This study was conducted 100 6 12 years tonsillectomy. Patients were randomly allocated into Group M D. Patient group (50) received 0.2mg/kg administered intranasally nasal drop using 1ml insulin syringe similarly D 1µg/kg drops syringe. Sedation score, Anxiolysis mask induction post-operative agitation score assessed. Satisfactory sedation achieved by 86% 68% respectively p (0.03). 84% 70% (0.09). In terms post op there no difference both (0.30). During time between administration pre drugs initiation anaesthesia, seems develop hypotension, hypoxia or any other life-threatening complication our we concluded that decreasing at parental found equally effective. However, Intranasal produced superior scores compared oral patients.